WSEAS Transactions on Biology and Biomedicine


Print ISSN: 1109-9518
E-ISSN: 2224-2902

Volume 15, 2018

Notice: As of 2014 and for the forthcoming years, the publication frequency/periodicity of WSEAS Journals is adapted to the 'continuously updated' model. What this means is that instead of being separated into issues, new papers will be added on a continuous basis, allowing a more regular flow and shorter publication times. The papers will appear in reverse order, therefore the most recent one will be on top.


Comparison of Different Methods of Glomerular Filtration Rate in Young Males with Arterial Hypertension

AUTHORS: Elena V. Pereverzeva, Anastasiya Yu. Gulko, Yury E. Vabishevich, Menizibeya O. Welcome, Anatoly V. Sikorsky, Vladimir A. Pereverzev

Download as PDF

ABSTRACT: Glomerular filtration rate (GFR) was investigated with different methods in hypertensive young men (18- 27 years) who never had primary disease of the kidney. GFR was evaluated by Rehberg method, Cockcroft-Gault formula, MDRD (Modification of diet in renal disease) formula, MDPvD (methylenedioxypyrovalerone) formula, CKD-EPI (Chronic Kidney Disease Epidemiology Collaboration) formula. The normalization of GFR to a standardized body surface area of 1.73 m2. The study showed no significant difference in the mean values of GFR calculated by Rehberg and Cockcroft-Gault formula. The GFR obtained by MDRD, MDPvD, CKD-EPI were respectively lower by 15.5%, 15.6% and 10.0%, compared with the result of the Rehberg method. Similar result was obtained when compared with the values calculated by the Cokcroft-Gault formula: GFR calculated by MDRD, MDPvD, CKD-EPI were respectively lower by 16.0%, 16.1% and 10.4%, respectively. In conclusion, GFR can better be determined in first degree hypertensive patients using Rehberg method or the Cokcroft Gault formula.

KEYWORDS: Glomerular filtration rate; Cockcroft-Gault; MDRD; MDPvD; CKD-EPI

REFERENCES:

[1] E. V. Shlyakhto, A. O. Konradi, N. E. Zvartau, “Arterial hypertension. Cardiology: national reference,” 2 nd ed., Ed. E. V. Shlyakhto. Moscow, GEOTAR-Media, 2015.

[2] V. P. Tsaryov, “Laboratory workshop on propaedeutics of internal diseases,” Minsk, BSMU press, 2004.

[3] R. G. Oganov, M. N. Mamedov, “National clinical recommendations,” Moscow, Russian Scientific Society of Cardiology, 2009.

[4] A. V. Smirnov, E. M. Shilov, V. A. Dobronravov, “National recommendations. Chronic kidney disease: the basic principles of screening, diagnosis, prevention, and approaches to treatment,” Clin. Nephrol., no. 4, pp.4-26, 2012.

[5] D. W. Cockroft, M. H. Gault, “Prediction of creatine cleareance from serum creatitnine,” Nefron, vol. 16, no. 1, pp. 31-41, 1976.

[6] M. H. Gault, “Predicting glomerular function from adjusted serum creatinine,” Nefron, no. 2, pp. 249- 256, 1992.

[7] K. Matsushita, B. K. Mahmodi, M. Woodward et al. , “Comparison of the risk prediction using the CKDEPI equation and the MDRD study equation for estimated glomerular filtration rate,” JAMA, vol. 307, pp. 1941-1951, 2012.

[8] A. A. Bova, “Chronic renal failure and chronic kidney disease: correlation of terms,” Military Med., no. 1, pp. 25-34, 2012.

[9] V. M. Zaitsev, V. G. Liflyandsky, V. I. Marinkin, “Applied medical statistics,” Foliant, St. Petersburg, 2006.

WSEAS Transactions on Biology and Biomedicine, ISSN / E-ISSN: 1109-9518 / 2224-2902, Volume 15, 2018, Art. #13, pp. 119-124


Copyright Β© 2018 Author(s) retain the copyright of this article. This article is published under the terms of the Creative Commons Attribution License 4.0

Bulletin Board

Currently:

The editorial board is accepting papers.


WSEAS Main Site