Plenary Lecture
Biomedical Applications of Gold Nanoparticles
Professor Vadim V. Sumbayev
Medway School of Pharmacy
University of Kent
United Kingdom
E-mail: V.Sumbayev@kent.ac.uk
Abstract: Gold nanoparticles display unique properties which allow them to influence different kinds of biochemical processes. Interestingly, these effects are particle size-dependent and are most likely caused by a particle surface. Gold nanoparticle surface properties as well as their biological effects vary based on their size, which determines the properties of nanomaterial surface. In addition, unlike most of other nanomaterials, gold nanoparticles do not trigger formation of pro-inflammatory multiprotein complexes, known as inflammasomes. Furthermore, they display clear anti-inflammatory activity. Here we discuss biological effects of intact and functionalised gold nanoparticles analysing their possible biochemical mechanisms.
Brief Biography of the Speaker: I obtained my PhD degree in Biochemistry in 1999 in Palladin Institute of Biochemistry NAS of UKraine. Then worked as assistant/associate professor at the Department of Biochemistry, Mechnikoff Odessa National University. In 2001 I obtained a highly competitive Humboldt Research Fellowship and moved to Germany (University of Kaiserslautern). Upon completion of my fellowship I spent three years in Aarhus (Denmark) working as assistant professor at the Interdisciplinary Nanoscience Centre, University of Aarhus. In December 2006 I joined Medway School of Pharmacy as a lecturer in Biochemistry.